Family at your wedding is important

I had gotten some news from my mom that is not sitting easy with me. I am the first born and have never been officially married but my sister has been 2 this would have been her 3rd and yes my mom has been to every single 1.Now since now my younger sister isnt getting married anymore. My moms tells me that she has to wait and see if her doctor will let her come up here for mine. When she said it felt like I got stab in the heart it's bad enough that my grandmother will not be here in the flesh but by spirit. See she passed away a year ago so that in it self is hard at times to deal with. Now I wont have that many family members present besides my kids a cushion or two. And some close friends I need my mom to be there with on my one big day. My sister and her is a couple of towns away from each other and I leave in north Jersey. I just hope and pray that she isn't telling me this because she is no longer getting married. And that this a medical thing and her doctor let her. But I have made measures for her and my FMIL where they would not have to worry about stairs easy access to the bathroom venue even for my hotel if she had to stay with me. Is there anyone else worried about that 1 family member or that important person either will be there or not. Because I have another 1 who may not come and that's my uncle he help raise me and since my grandmother passed he has been distance and unemotional towards me.I didn't want to really mentioned it but for this will feel uneasy. But I am still getting married no matter what it would have like them to be there and yes I have sent a invitation an no answer.😢